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Fund Africa researchers to sustain fight against HIV despite aid cuts
Although nearly half of the 40.8 million people estimated to be living with HIV around the world in 2024 came from Africa, only a fraction of every research dollar spent globally went to African institutions.
For decades, Africa’s role in HIV research has been framed as that of a peripheral host, not driver, but that era is over, as showcased at the recently concluded International Aids Society (IAS) conference in Kigali.
African scientists are now playing a significant role in accelerating the global search for an effective HIV vaccine—designing clinical trials, and testing whether new treatments or vaccines are safe and effective in people.
Recently, for instance, International AIDS Vaccine Initiative (IAVI), a global non-profit scientific research oganisation, announced that the initial doses of an investigational HIV vaccine candidate have been administered as part of a Phase I clinical trial underway in South Africa and Zimbabwe.
The trial aims to evaluate the safety and immune response of the vaccine candidate, known as the Gorilla Adenovirus Vectored HIV Networked Epitopes Vaccine, in individuals with and without HIV.
This landmark trial has not only transformed scientific approaches but also galvanised a broader movement toward African scientific ownership, reshaping how HIV prevention research is conducted worldwide.
However, while these clinical trials and advances in biomedical research offer hope, their reach and impact are still very limited, due to barriers such as a lack of access to sufficient research funding.
Although nearly half of the 40.8 million people estimated to be living with HIV around the world in 2024 came from Africa, only a fraction of every research dollar spent globally went to African institutions.
Civil society voices continue to demand answers, exposing how promises of “shared responsibility” often mask persistent inequities in access and delivery.
Scientific breakthroughs mean very little if they do not reach those who need them most. That is why we must start to examine whether current models of “global solidarity” truly serve African communities.
Real progress cannot be attained through symbolic inclusion, but rather through genuine investment in African scientific capacity.
We must strengthen local institutions and embed community-led science across all levels.
By investing in Africa’s research and implementation capacity, we not only accelerate access to life-saving innovations but also ensure that health priorities are shaped by those who understand these needs best.
When research is well conducted locally, the solutions are more likely to be effective and efficient because they are grounded in real challenges, contextually relevant, and culturally appropriate and sustainable.
This leads to better policy alignment, faster responses to emerging threats, and a reduction in mortality and morbidity across the board.
The writer is the Founder and Chief Executive Officer of the Centre for Impact, Innovation and Capacity building for Health Information systems and Nutrition (CIIC-HIN)
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